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EpioxaCareConnect™ is the one place for all the support you need

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EpioxaCareConnect is a free program that supports you
throughout your treatment journey

Connect with a dedicated Patient Access Liaison (PAL) who can:

  • Provide 1-on-1 non-medical education and support during your Epioxa treatment journey
  • Help you understand your insurance coverage
  • Explain and answer questions about the Epioxa procedure
  • Share information about financial assistance programs

You may pay as little as $0* for Epioxa treatment

Learn about support program

*For eligible people who are commercially insured.

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Discussing Epioxa treatment with your doctor

Here are some helpful questions to ask your doctor to get the conversation about Epioxa treatment started:

  • What should I know about the potential side effects of Epioxa treatment?

    The most common side effects associated with Epioxa treatment were: red eye, haze, sensitivity to light, disruption of surface cells of the cornea, eye pain, eye irritation, watery eyes, swelling of eyelid, fine white lines in the cornea, reduced sharpness of vision, dry eye, and eye inflammation.
  • How soon after treatment for my first eye can I receive treatment for my second eye?

    In the clinical trials, some people got their second eye treated as soon as 1 week after their first treatment. Make sure to work with your doctor to monitor your recovery and to plan your next procedure.
  • Will I still need to wear glasses or contact lenses after the procedure?

    Some people may still have to wear glasses or contact lenses to correct their vision after receiving Epioxa treatment. Your doctor will help you determine your vision correction needs and any ongoing eye care after the procedure.

Download these resources for more information on what programs are available to support your treatment journey

EpioxaCareConnect PAL Brochure cover sheet

EpioxaCareConnect Brochure

An overview of patient support offerings available through the EpioxaCareConnect program.

Download the brochure
Understanding Insurance Coverage cover sheet

Insurance Explained Guide

A brochure to guide you through insurance coverage and approval of Epioxa.

Download the guide
Epioxa Copay Assistance Program FAQs-Talking Points cover sheet

Copay Assistance Brochure

An overview of the copay assistance program available to eligible patients with commercial insurance.

Download the brochure

Frequently asked questions

  • What is keratoconus?

    Keratoconus is a progressive disease that causes the cornea to thin and become cone-shaped, leading to visual distortion and, in advanced cases, severe visual impairment.
  • How do I say Epioxa?

    eh-pee-OX-ah
  • What is Epioxa?

    Epioxa is the only FDA approved, epithelium-on, oxygen-enriched, corneal cross-linking treatment for keratoconus.
  • How is Epioxa different from other treatments for keratoconus?

    Epioxa is the first and only epithelium-on, corneal cross-linking treatment that is approved by the FDA to treat keratoconus.
  • Who is eligible for Epioxa?

    Epioxa is approved to treat keratoconus in adults and pediatric patients aged 13 years and older.
  • Is Epioxa safe and effective to treat keratoconus?

    Yes, the safety and efficacy of Epioxa were studied in 2 prospective, multicentered, randomized 2:1 sham procedure/placebo-controlled clinical trials, and was approved by the FDA for the treatment of keratoconus in adults and pediatric patients aged 13 years and older. For complete information, review the full Prescribing Information and discuss with your doctor.
  • What support programs are available for those patients who are interested in treatment with Epioxa?

    Glaukos is committed to ensuring all eligible patients have access to treatment with Epioxa. Beginning in January 2026, patient assistance programs will be available for eligible patients.

IMPORTANT SAFETY INFORMATION

The most common side effects were red eye, haze, sensitivity to light, disruption of surface cells of the cornea, eye pain, eye irritation, watery eyes, swelling of eyelid, fine white lines in the cornea, reduced sharpness of vision, dry eye, and eye inflammation.

You should not have the EPIOXA™ corneal collagen cross-linking procedure if you have a known hypersensitivity to any ingredients in the product, have had cataract surgery and either did not receive an artificial lens in your eye or received a non-UV blocking artificial lens, have a history of herpetic keratitis, or are pregnant.

If you have any additional questions, please contact your doctor. Please see full Prescribing Information for EPIOXA HD and EPIOXA.

You are encouraged to report all side effects to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also call Glaukos at 1-888-404-1644.

APPROVED USES

The EPIOXA corneal collagen cross-linking procedure is performed by your eye doctor for the treatment of keratoconus. It does not require the removal of the corneal epithelium (outermost layer of the front of the eye). It consists of EPIOXA™ HD (riboflavin 5′-phosphate ophthalmic solution) 0.239% and EPIOXA™ (riboflavin 5′-phosphate ophthalmic solution) 0.177%, which are prescription eye drops used in combination with the O2n™ System and Boost Goggles®.

The EPIOXA corneal collagen cross-linking procedure is for the treatment of keratoconus in adults and pediatric patients 13 years of age and older.